Deep dives into peptides, hormones, nutrition, and everything you need to optimize your health.
A clear, grounded primer on what peptides are, why they've become mainstream in the wellness conversation, and what to keep in mind before exploring the space.
Should you start with hormone replacement therapy or GLP-1s first? Hunter Williams breaks down why the answer might surprise you — and why both paths can work.
Most people use GHK-Cu for skin and hair. A new preprint from the University of Washington shows intranasal GHK-Cu improves spatial learning in aged mice and suppresses the same pathways as rapamycin and caloric restriction.
Hunter answers 37 listener questions covering kisspeptin for women on TRT, optimal estrogen targets, PCOS protocols, GHK-Cu injection tips, PEG-MGF, stacking tirzepatide and retatrutide, MK-677 vs MK-777, and much more.
Some people get hungrier on retatrutide — not less hungry. Here's the TRIUMPH-4 trial data that explains why, and exactly what to do about it.
The FDA just removed BPC-157, TB-500, KPV, MOTS-c, Semax, Epitalon, and six other peptides from Category 2. Here's what actually happened, what comes next, and what it means for how you access peptides.
A critical, evidence-based analysis of a Harvard-led study that looked at tesamorelin's effects on cancer-related gene expression in the liver — and what it means for anyone using or considering GH peptides.
Spermidine has a strange name, but the research behind it is serious. Hunter Williams breaks down how it triggers autophagy, mimics fasting signals, and what dose actually moves the needle.
One of the most common things men get scared about on TRT is rising hematocrit. Here's what it actually means, when to worry, and why routine blood donation may be doing more harm than good.
A landmark BMJ study of over 600,000 veterans found that GLP-1 drugs reduced substance use disorder risk by 14% across alcohol, nicotine, cocaine, cannabis, and opioids — and cut overdose deaths by 50% in those already addicted.
Spermidine activates autophagy, clears damaged mitochondria, and makes your NAD+ supplementation actually work. Here's the science behind one of longevity medicine's most underrated compounds.
GLP-1 agonists are transforming metabolic health — but some users report a troubling side effect: emotional numbness and loss of joy. Here's the mechanism behind GLP-1-induced anhedonia and what you can do about it.
A preclinical study presented at the Society for Immunotherapy of Cancer found that low-dose retatrutide reduced pancreatic tumor growth to a degree comparable to anti-PD1 immunotherapy — without significant weight loss. Here's what that means for longevity.
If you aren't using BPC-157 and TB-500 to address the structural integrity of your tendons, you aren't training—you're just waiting for a tear.
I was 24 years old with the testosterone levels of an 80-year-old man. In 2026, we know that 'Normal' is just a statistical average of an increasingly sick population.
Football gave me a lot, but it took a toll on my gray matter. If you've ever felt that 'static' in your head, you're dealing with chronic neuro-inflammation.
